Double Digest Restriction Associated DNA (ddRAD) Sequencing

Laboratories such as, MRDNA, are gravitating towards the use of double digest RAD-Seq (ddRAD-Seq) approach for genotyping. In this method, genomic DNA is digested with two restriction enzymes, and the resulting fragments undergo adaptor ligations and precise size selection before sequencing. This method permits high throughput simultaneous discovery and genotyping of sequence polymorphism either with […]

Whole Exome Sequencing

Exome sequencing is a strategy to selectively sequence the coding regions of the genome. In the human genome, exons constitute about 1% of its genome and that the protein coding regions of the human genome constitute about 85% of the disease-causing mutations. MRDNA uses TruSeq exome enrichment kit (Illumina) for the sample library preparation. Sequence data generated […]

ChIP-Seq (Chromatin immunoprecipitation sequencing)

Chromatin immunoprecipitation (ChIP) is a powerful method for studying interactions between specific proteins and a genomic DNA region. MRDNA routinely performs ChIP-seq and provide cost effective high quality data, global binding site maps for a protein of interest and robust output. Please visit               Our services – MR […]

Genome Sequencing Service

Genome sequencing is described as the process of determining the order of the nucleotide bases within a certain length strand of DNA. You can sequence a short piece, the whole genome, or parts of the genome (exomes – parts of the genome that contain genes). The knowledgeable team at MR DNA Lab (also known as […]

#DNA on Twitter

Tweet-tweet! Nowadays, Twitter is not merely a social-network. It has become a must-read source of real-time industry news and information with regular updates, news and discussions from the leading minds of today. The advent of Twitter has allowed for folks to have real-time conversations with thought leaders across the field. An upcoming researcher in genomics […]

Microbial Communities: Microbiome, Metagenome, Microbiota

What consists of microbial communities analysis? Microbiome and microbiota explain the collective genomes of the microorganisms that inhabit an environmental niche or the microorganisms themselves. Microbiota are the microorganisms present within a particular environment. The approach to describe microbial diversity relies on analyzing the gene diversity 16S ribosomal RNA (16S rRNA) through next-generation sequencing. The […]

Next-Generation Sequencing Services (DNA)

Scientists are now able to elucidate the microbiome of human diseases, agricultural and other natural, environments. Especially at MR DNA Lab, scientists are dedicated to microbiome research. Their method development has opened doors to research around the world. This initiative is one component of the MR DNA program and constitutes a major NIH effort to […]

Organic Molecules: Nucleic Acids (RNA and DNA)

Organic molecules are classified in four classes: carbs, lipids, proteins, and last but not least nucleic acids. There are two principle nucleic acids, ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). DNA is a double polymer of nucleotides, whereas RNA is only once strand. RNA strands are substantially shorter than DNA. The reason why DNA strands […]

DNA Gets Social

With over 200 million users, Twitter has emerged as a viable medium for determining influence in many fields – including the field of science. Scientists from all over the world are taking to Twitter to spread the ideas and information to followers. Social media teams, like the one at MR DNA Lab, have added Twitter […]

Understanding the 454 Method

A DNA strand is prepared by cutting the sample into small fragmented pieces (Fig 1). Attached to the ends of these fragments are oligonucleotide adaptors (Fig 2). These allow the fragments to individually attach to primer-coated beads. The goal is to have one fragment per bead. Amplification essentially copies fragments on each bead (Fig 3). […]